Focusing MicroRNAs in Cancer Gene Therapy
Oncology-miRNA
Keywords:
miRNA, miRNA dysregulation, ancer cell lines, Breast Cancer, carcinogenesisAbstract
Non-coding RNAs, also known as microRNAs (miRNAs), emphasize an assortment of molecules to influence the synthesis of genes. Initial research has demonstrated that various tumor tissues and cancer cell lines exhibit large variations in miRNA expression. Practically every biological procedure, namely cell division, movement, survival, and differentiation, is known to entail such diversity. A growing body of experimental evidence suggests that miRNA dysregulation is a biomarker for a series of clinical illnesses, including cancer, and that miRNA may have a causative role, acting as oncogenes or tumour regulator genes, at various stages of the tumorigenic process. Anticancer medicines based on miRNAs are currently being created to enhance the effectiveness of cancer treatment. The interference of miRNAs in carcinogenesis and growth is reviewed in this study review, and the latest clinical possibilities and treatment plans aimed at miRNAs in cancer are also covered. Our review focuses on breast cancer, lung cancer, gastric cancer, prostate cancer, and Hepatocellular Carcinoma.
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